What happens when abiraterone stops working?
When abiraterone, a drug commonly used to treat metastatic prostate cancer, stops working, it means the cancer has become resistant to the drug. Abiraterone works by blocking the production of androgens (male hormones such as testosterone), which prostate cancer cells often rely on to grow. However, over time, prostate cancer cells can adapt and adopt ways to grow despite low androgen levels. When this happens, the cancer can continue to progress, and the following things can happen: Cancer progression: The tumor may begin to grow again, causing an increase in symptoms or an increase in PSA (prostate-specific antigen) levels, a marker used to monitor the progression of prostate cancer and Abiraterone Price in Malaysia . Development of resistance: This resistance can be caused by several factors, including: Alternative androgen production: Prostate cancer cells may develop mechanisms to produce their own androgens or activate androgen receptors even without external androgens. Mutations...